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Orthopedic Bone Cement-Medical Devices Pipeline Assessment, 2017

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Details

Orthopedic Bone Cement-Medical Devices Pipeline Assessment, 2017

Summary

GlobalData's Medical Devices sector report, "Orthopedic Bone Cement-Medical Devices Pipeline Assessment, 2017" provides an overview of Orthopedic Bone Cement currently in pipeline stage.

The report provides comprehensive information on the pipeline products with comparative analysis of the products at various stages of development. The report reviews major players involved in the pipeline product development. It also provides information about clinical trials in progress, which includes trial phase, trial status, trial start and end dates, and the number of trials for the key Orthopedic Bone Cement pipeline products.

This report is prepared using data sourced from in-house databases, secondary and primary research by GlobalData's team of industry experts.

*Note: Certain sections in the report may be removed or altered based on the availability and relevance of data in relation to the equipment type.

Scope

Extensive coverage of the Orthopedic Bone Cement under development

The report reviews details of major pipeline products which includes, product description, licensing and collaboration details and other developmental activities

The report reviews the major players involved in the development of Orthopedic Bone Cement and list all their pipeline projects

The coverage of pipeline products based on various stages of development ranging from Early Development to Approved / Issued stage

The report provides key clinical trial data of ongoing trials specific to pipeline products

Recent developments in the segment / industry

Reasons to Buy

The report enables you to-

Formulate significant competitor information, analysis, and insights to improve R&D strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Identify and understand important and diverse types of Orthopedic Bone Cement under development

Develop market-entry and market expansion strategies

Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline

In-depth analysis of the product's current stage of development, territory and estimated launch date

READ MORE

Table Of Content

Scope

1 Table of Contents

1 Table of Contents 2

1.1 List of Tables 5

1.2 List of Figures 6

2 Introduction 7

2.1 Orthopedic Bone Cement Overview 7

3 Products under Development 8

3.1 Orthopedic Bone Cement-Pipeline Products by Stage of Development 8

3.2 Orthopedic Bone Cement-Pipeline Products by Segment 9

3.3 Orthopedic Bone Cement-Pipeline Products by Territory 10

3.4 Orthopedic Bone Cement-Pipeline Products by Regulatory Path 11

3.5 Orthopedic Bone Cement-Pipeline Products by Estimated Approval Date 12

4 Orthopedic Bone Cement-Pipeline Products under Development by Companies 13

4.1 Orthopedic Bone Cement Companies-Pipeline Products by Stage of Development 13

4.2 Orthopedic Bone Cement-Pipeline Products by Stage of Development 14

5 Orthopedic Bone Cement Companies and Product Overview 15

5.1 aap Implantate AG Company Overview 15

5.1.1 aap Implantate AG Pipeline Products & Ongoing Clinical Trials Overview 15

5.2 Biofix Medical Technologies Company Overview 17

5.2.1 Biofix Medical Technologies Pipeline Products & Ongoing Clinical Trials Overview 17

5.3 Bone-Rad Therapeutics, Inc. Company Overview 18

5.3.1 Bone-Rad Therapeutics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 18

5.4 DePuy Synthes Inc Company Overview 19

5.4.1 DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview 19

5.5 Exactech Inc Company Overview 20

5.5.1 Exactech Inc Pipeline Products & Ongoing Clinical Trials Overview 20

5.6 Graftys SA Company Overview 21

5.6.1 Graftys SA Pipeline Products & Ongoing Clinical Trials Overview 21

5.7 Meta Biomed Co Ltd Company Overview 23

5.7.1 Meta Biomed Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 23

5.8 Onbone Oy Company Overview 24

5.8.1 Onbone Oy Pipeline Products & Ongoing Clinical Trials Overview 24

5.9 Osseon Therapeutics Inc Company Overview 25

5.9.1 Osseon Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 25

5.10 Ozics AG Company Overview 26

5.10.1 Ozics AG Pipeline Products & Ongoing Clinical Trials Overview 26

5.11 Queen's University Belfast Company Overview 28

5.11.1 Queen's University Belfast Pipeline Products & Ongoing Clinical Trials Overview 28

5.12 Sree Chitra Tirunal Institute for Medical Sciences & Technology Company Overview 29

5.12.1 Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 29

5.13 Teknimed SA Company Overview 32

5.13.1 Teknimed SA Pipeline Products & Ongoing Clinical Trials Overview 32

5.14 University of Limerick Company Overview 34

5.14.1 University of Limerick Pipeline Products & Ongoing Clinical Trials Overview 34

5.15 Zimmer Biomet Holdings Inc Company Overview 36

5.15.1 Zimmer Biomet Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 36

6 Orthopedic Bone Cement- Recent Developments 37

6.1 Mar 21, 2017: Medtronic Prices Public Offering of 1.7% Notes Due 2019 for USD1 Billion 37

6.2 Mar 21, 2017: Medtronic Prices Public Offering of 3.35% Notes Due 2027 for USD850 Million 37

6.3 Mar 21, 2017: Medtronic Prices Public Offering of 4.625% Notes Due 2045 for USD150 Million 38

6.4 Mar 15, 2017: Alphatec Holdings Announces Fourth Quarter and Full Year 2016 Financial Results 38

6.5 Mar 14, 2017: Medtronic Announces New Bone Cement Indication for Treating Sacral Fractures 39

6.6 Mar 08, 2017: DJO Global Announces Financial Results for Fourth Quarter and Fiscal Year End 2016 40

6.7 Mar 01, 2017: DJO Global Announces Appointment of Bryan McMillan as President, Regeneration 43

6.8 Feb 21, 2017: Medtronic Reports Third Quarter Financial Results 43

6.9 Feb 21, 2017: Exactech 2016 Revenue Up 7% to $257.6 Million, Q4'16 Revenue Increased 6% to $66.2 Million 46

6.10 Feb 14, 2017: Alphatec Spine Announces Appointment of David H. Mowry to its Board of Directors 48

6.11 Feb 09, 2017: Smith & Nephew Fourth Quarter Trading and Full Year 2016 Results 48

6.12 Feb 09, 2017: Smith & Nephew: Directorate Change 54

6.13 Feb 06, 2017: Medtronic Awarded U.S. Department of Veterans Affairs National Contracts for Home Telehealth Technologies, with Three Other Vendors 54

6.14 Jan 31, 2017: Zimmer Biomet Reports Fourth Quarter and Full-Year 2016 Financial Results 55

6.15 Jan 24, 2017: Stryker reports 2016 results and 2017 outlook 56

6.16 Jan 17, 2017: Zimmer Biomet Announces Americas Leadership Transition 57

6.17 Jan 12, 2017: Stryker Prices Public Offering of 1.800% Notes Due 2019 for USD500 Million 58

6.18 Jan 12, 2017: Zimmer Biomet Announces Resolution with DOJ and SEC Regarding Previously Disclosed Legacy Biomet FCPA Matters 58

6.19 Jan 12, 2017: Confirmation of CFO leaving Smith & Nephew 58

6.20 Jan 10, 2017: Stryker provides 2016 preliminary net sales results 59

6.21 Jan 10, 2017: Zimmer Biomet Announces Fourth Quarter and Full-Year 2016 Preliminary Sales Results 60

6.22 Dec 14, 2016: Zimmer Biomet Update on Product Supply Matters and Responsive Statement on Recently Completed FDA Inspection 61

6.23 Dec 12, 2016: Alphatec Holdings appoints new CEO 61

6.24 Dec 12, 2016: Alphatec Holdings Announces Board and Executive Leadership Changes 62

6.25 Nov 30, 2016: Graham Baker appointed Chief Financial Officer 65

6.26 Nov 22, 2016: Medtronic Reports Second Quarter Financial Results 65

6.27 Nov 16, 2016: Medtronic Releases FY16 Integrated Performance Report 68

6.28 Nov 15, 2016: CEVA to work with Medtronic for distribution facility construction 69

6.29 Nov 14, 2016: DJO Global Announces Appointment of Brady Shirley as President and Chief Executive Officer 69

6.30 Nov 09, 2016: Alphatec Holdings Announces Third Quarter 2016 Revenue and Financial Results 70

6.31 Nov 08, 2016: DJO Global Announces Financial Results for Third Quarter 73

6.32 Nov 03, 2016: Smith & Nephew Third Quarter 2016 Trading Report 74

6.33 Oct 31, 2016: Zimmer Biomet Reports Third Quarter 2016 Financial Results 76

6.34 Oct 31, 2016: Exactech Q3 Revenue Up 7% to $59.9 Million. Net Income up 10% to $3.2 Million. Diluted EPS $0.22 vs. $0.20. 77

6.35 Oct 27, 2016: Stryker reports third quarter 2016 results 78

6.36 Oct 05, 2016: Alphatec Holdings Announces Company Updates 79

6.37 Sep 15, 2016: Alphatec Holdings Announces Company Updates 80

6.38 Sep 15, 2016: Medtronic Names Mark Ploof Senior Vice President of Global Operations and Business Services 82

6.39 Sep 06, 2016: DJO Global Announces Appointment of Mike Eklund as Chief Operating Officer and Chief Financial Officer 82

6.40 Aug 25, 2016: Medtronic Reports First Quarter Financial Results 83

6.41 Aug 01, 2016: Exactech Q2 Revenue Up 8% to $66.1 Million; Net Income up 20% to $4.4 Million; Diluted EPS $0.31 vs. $0.26 86

6.42 Jul 28, 2016: Smith & Nephew Second Quarter Trading and First Half 2016 Results 87

6.43 Jul 28, 2016: Zimmer Biomet Reports Second Quarter 2016 Financial Results 90

6.44 Jul 28, 2016: DJO Global Announces Financial Results for Second Quarter 2016 91

6.45 Jul 21, 2016: Stryker reports second quarter 2016 results 92

6.46 Jul 11, 2016: CFO to leave Smith & Nephew in early 2017 93

6.47 Jul 06, 2016: Merit Medical Systems Acquires DFINE for USD97.5 Million 94

6.48 Jun 30, 2016: NuVasive Agrees to Settle Patent Litigation With Medtronic 94

6.49 Jun 13, 2016: Zimmer Biomet Raises USD1.28 Billion in Public Offering of Shares 95

6.50 Jun 07, 2016: Zimmer Biomet Raises USD532 Million in Public Offering of 2.42% Notes Due 2026 95

6.51 Jun 07, 2016: Zimmer Biomet Raises USD532 Million in Public Offering of 1.4% Notes Due 2022 96

6.52 Jun 06, 2016: Medtronic Outlines Future Growth Vision at Investor Day 96

6.53 Jun 01, 2016: Osseon Expands Its Independent Distribution Network 97

6.54 May 31, 2016: Medtronic Reports Fourth Quarter and Fiscal Year 2016 Financial Results 97

6.55 May 10, 2016: DJO Global Announces Financial Results for First Quarter 2016 100

6.56 Apr 20, 2016: Stryker reports first quarter 2016 results 101

6.57 Mar 31, 2016: GRAFTYS strengthens its management and operations 102

7 Appendix 103

7.1 Methodology 103

7.2 About GlobalData 106

7.3 Contact Us 106

7.4 Disclaimer 106


List Of Figure

1.2 List of Figures

Figure 1: Orthopedic Bone Cement-Pipeline Products by Stage of Development 8

Figure 2: Orthopedic Bone Cement-Pipeline Products by Segment 9

Figure 3: Orthopedic Bone Cement-Pipeline Products by Territory 10

Figure 4: Orthopedic Bone Cement-Pipeline Products by Regulatory Path 11

Figure 5: Orthopedic Bone Cement-Pipeline Products by Estimated Approval Date 12


List Of Table

1.1 List of Tables

Table 1: Orthopedic Bone Cement-Pipeline Products by Stage of Development 8

Table 2: Orthopedic Bone Cement-Pipeline Products by Segment 9

Table 3: Orthopedic Bone Cement-Pipeline Products by Territory 10

Table 4: Orthopedic Bone Cement-Pipeline Products by Regulatory Path 11

Table 5: Orthopedic Bone Cement-Pipeline Products by Estimated Approval Date 12

Table 6: Bone Cement Companies-Pipeline Products by Stage of Development 13

Table 7: Orthopedic Bone Cement-Pipeline Products by Stage of Development 14

Table 8: aap Implantate AG Pipeline Products & Ongoing Clinical Trials Overview 15

Table 9: Ag Cement-Product Status 15

Table 10: Ag Cement-Product Description 16

Table 11: Biofix Medical Technologies Pipeline Products & Ongoing Clinical Trials Overview 17

Table 12: Injectable Glass Ionomer Cement-Product Status 17

Table 13: Injectable Glass Ionomer Cement-Product Description 17

Table 14: Bone-Rad Therapeutics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 18

Table 15: Spine-Rad Brachytherapy Bone Cement-Product Status 18

Table 16: Spine-Rad Brachytherapy Bone Cement-Product Description 18

Table 17: DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview 19

Table 18: Statin Eluting Bone Cements-Product Status 19

Table 19: Statin Eluting Bone Cements-Product Description 19

Table 20: Exactech Inc Pipeline Products & Ongoing Clinical Trials Overview 20

Table 21: Bone Cement-Product Status 20

Table 22: Bone Cement-Product Description 20

Table 23: Graftys SA Pipeline Products & Ongoing Clinical Trials Overview 21

Table 24: GRFT-M03-Product Status 21

Table 25: GRFT-M03-Product Description 21

Table 26: GRFT-M05-Product Status 22

Table 27: GRFT-M05-Product Description 22

Table 28: Meta Biomed Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 23

Table 29: Bone Cement-Product Status 23

Table 30: Bone Cement-Product Description 23

Table 31: Onbone Oy Pipeline Products & Ongoing Clinical Trials Overview 24

Table 32: BIOCEMENT-Product Status 24

Table 33: BIOCEMENT-Product Description 24

Table 34: Osseon Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 25

Table 35: Monetite-Based Injectable Orthopaedic Cement-Product Status 25

Table 36: Monetite-Based Injectable Orthopaedic Cement-Product Description 25

Table 37: Ozics AG Pipeline Products & Ongoing Clinical Trials Overview 26

Table 38: CompO6 Bone Reinforcement Composite-Product Status 26

Table 39: CompO6 Bone Reinforcement Composite-Product Description 26

Table 40: CompO6 Reinforced Bone Composite-Osteoporotic Fractures-Product Status 27

Table 41: CompO6 Reinforced Bone Composite-Osteoporotic Fractures-Product Description 27

Table 42: Queen's University Belfast Pipeline Products & Ongoing Clinical Trials Overview 28

Table 43: Spinal Cement-Product Status 28

Table 44: Spinal Cement-Product Description 28

Table 45: Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 29

Table 46: BioCaS-Product Status 29

Table 47: BioCaS-Product Description 29

Table 48: Bone Cement-Product Status 30

Table 49: Bone Cement-Product Description 30

Table 50: Injectable Calcium Phosphate Cement-Product Status 30

Table 51: Injectable Calcium Phosphate Cement-Product Description 31

Table 52: Teknimed SA Pipeline Products & Ongoing Clinical Trials Overview 32

Table 53: Cemfix 1-Product Status 32

Table 54: Cemfix 1-Product Description 32

Table 55: Cemfix 3-Product Status 33

Table 56: Cemfix 3-Product Description 33

Table 57: University of Limerick Pipeline Products & Ongoing Clinical Trials Overview 34

Table 58: Bioactive Adhesive Cement-Product Status 34

Table 59: Bioactive Adhesive Cement-Product Description 34

Table 60: Dual Calcium Phosphate Paste System-Product Status 34

Table 61: Dual Calcium Phosphate Paste System-Product Description 35

Table 62: Heracap-Product Status 35

Table 63: Heracap-Product Description 35

Table 64: Zimmer Biomet Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 36

Table 65: Cobalt Stage One Acrylic Spacer Cement-Product Status 36

Table 66: Cobalt Stage One Acrylic Spacer Cement-Product Description 36

Table 67: Glossary 105

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Products and Companies


Companies

aap Implantate AG, Biofix Medical Technologies, Bone-Rad Therapeutics, Inc., DePuy Synthes Inc, Exactech Inc, Graftys SA, Meta Biomed Co Ltd, Onbone Oy, Osseon Therapeutics Inc, Ozics AG, Queen's University Belfast, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Teknimed SA, University of Limerick, Zimmer Biomet Holdings Inc

Company Profile

Company Profile Title

Orthopedic Bone Cement-Medical Devices Pipeline Assessment, 2017

Summary

GlobalData's Medical Devices sector report, "Orthopedic Bone Cement-Medical Devices Pipeline Assessment, 2017" provides an overview of Orthopedic Bone Cement currently in pipeline stage.

The report provides comprehensive information on the pipeline products with comparative analysis of the products at various stages of development. The report reviews major players involved in the pipeline product development. It also provides information about clinical trials in progress, which includes trial phase, trial status, trial start and end dates, and the number of trials for the key Orthopedic Bone Cement pipeline products.

This report is prepared using data sourced from in-house databases, secondary and primary research by GlobalData's team of industry experts.

*Note: Certain sections in the report may be removed or altered based on the availability and relevance of data in relation to the equipment type.

Scope

Extensive coverage of the Orthopedic Bone Cement under development

The report reviews details of major pipeline products which includes, product description, licensing and collaboration details and other developmental activities

The report reviews the major players involved in the development of Orthopedic Bone Cement and list all their pipeline projects

The coverage of pipeline products based on various stages of development ranging from Early Development to Approved / Issued stage

The report provides key clinical trial data of ongoing trials specific to pipeline products

Recent developments in the segment / industry

Reasons to Buy

The report enables you to-

Formulate significant competitor information, analysis, and insights to improve R&D strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Identify and understand important and diverse types of Orthopedic Bone Cement under development

Develop market-entry and market expansion strategies

Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline

In-depth analysis of the product's current stage of development, territory and estimated launch date

READ MORE

Scope

1 Table of Contents

1 Table of Contents 2

1.1 List of Tables 5

1.2 List of Figures 6

2 Introduction 7

2.1 Orthopedic Bone Cement Overview 7

3 Products under Development 8

3.1 Orthopedic Bone Cement-Pipeline Products by Stage of Development 8

3.2 Orthopedic Bone Cement-Pipeline Products by Segment 9

3.3 Orthopedic Bone Cement-Pipeline Products by Territory 10

3.4 Orthopedic Bone Cement-Pipeline Products by Regulatory Path 11

3.5 Orthopedic Bone Cement-Pipeline Products by Estimated Approval Date 12

4 Orthopedic Bone Cement-Pipeline Products under Development by Companies 13

4.1 Orthopedic Bone Cement Companies-Pipeline Products by Stage of Development 13

4.2 Orthopedic Bone Cement-Pipeline Products by Stage of Development 14

5 Orthopedic Bone Cement Companies and Product Overview 15

5.1 aap Implantate AG Company Overview 15

5.1.1 aap Implantate AG Pipeline Products & Ongoing Clinical Trials Overview 15

5.2 Biofix Medical Technologies Company Overview 17

5.2.1 Biofix Medical Technologies Pipeline Products & Ongoing Clinical Trials Overview 17

5.3 Bone-Rad Therapeutics, Inc. Company Overview 18

5.3.1 Bone-Rad Therapeutics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 18

5.4 DePuy Synthes Inc Company Overview 19

5.4.1 DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview 19

5.5 Exactech Inc Company Overview 20

5.5.1 Exactech Inc Pipeline Products & Ongoing Clinical Trials Overview 20

5.6 Graftys SA Company Overview 21

5.6.1 Graftys SA Pipeline Products & Ongoing Clinical Trials Overview 21

5.7 Meta Biomed Co Ltd Company Overview 23

5.7.1 Meta Biomed Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 23

5.8 Onbone Oy Company Overview 24

5.8.1 Onbone Oy Pipeline Products & Ongoing Clinical Trials Overview 24

5.9 Osseon Therapeutics Inc Company Overview 25

5.9.1 Osseon Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 25

5.10 Ozics AG Company Overview 26

5.10.1 Ozics AG Pipeline Products & Ongoing Clinical Trials Overview 26

5.11 Queen's University Belfast Company Overview 28

5.11.1 Queen's University Belfast Pipeline Products & Ongoing Clinical Trials Overview 28

5.12 Sree Chitra Tirunal Institute for Medical Sciences & Technology Company Overview 29

5.12.1 Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 29

5.13 Teknimed SA Company Overview 32

5.13.1 Teknimed SA Pipeline Products & Ongoing Clinical Trials Overview 32

5.14 University of Limerick Company Overview 34

5.14.1 University of Limerick Pipeline Products & Ongoing Clinical Trials Overview 34

5.15 Zimmer Biomet Holdings Inc Company Overview 36

5.15.1 Zimmer Biomet Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 36

6 Orthopedic Bone Cement- Recent Developments 37

6.1 Mar 21, 2017: Medtronic Prices Public Offering of 1.7% Notes Due 2019 for USD1 Billion 37

6.2 Mar 21, 2017: Medtronic Prices Public Offering of 3.35% Notes Due 2027 for USD850 Million 37

6.3 Mar 21, 2017: Medtronic Prices Public Offering of 4.625% Notes Due 2045 for USD150 Million 38

6.4 Mar 15, 2017: Alphatec Holdings Announces Fourth Quarter and Full Year 2016 Financial Results 38

6.5 Mar 14, 2017: Medtronic Announces New Bone Cement Indication for Treating Sacral Fractures 39

6.6 Mar 08, 2017: DJO Global Announces Financial Results for Fourth Quarter and Fiscal Year End 2016 40

6.7 Mar 01, 2017: DJO Global Announces Appointment of Bryan McMillan as President, Regeneration 43

6.8 Feb 21, 2017: Medtronic Reports Third Quarter Financial Results 43

6.9 Feb 21, 2017: Exactech 2016 Revenue Up 7% to $257.6 Million, Q4'16 Revenue Increased 6% to $66.2 Million 46

6.10 Feb 14, 2017: Alphatec Spine Announces Appointment of David H. Mowry to its Board of Directors 48

6.11 Feb 09, 2017: Smith & Nephew Fourth Quarter Trading and Full Year 2016 Results 48

6.12 Feb 09, 2017: Smith & Nephew: Directorate Change 54

6.13 Feb 06, 2017: Medtronic Awarded U.S. Department of Veterans Affairs National Contracts for Home Telehealth Technologies, with Three Other Vendors 54

6.14 Jan 31, 2017: Zimmer Biomet Reports Fourth Quarter and Full-Year 2016 Financial Results 55

6.15 Jan 24, 2017: Stryker reports 2016 results and 2017 outlook 56

6.16 Jan 17, 2017: Zimmer Biomet Announces Americas Leadership Transition 57

6.17 Jan 12, 2017: Stryker Prices Public Offering of 1.800% Notes Due 2019 for USD500 Million 58

6.18 Jan 12, 2017: Zimmer Biomet Announces Resolution with DOJ and SEC Regarding Previously Disclosed Legacy Biomet FCPA Matters 58

6.19 Jan 12, 2017: Confirmation of CFO leaving Smith & Nephew 58

6.20 Jan 10, 2017: Stryker provides 2016 preliminary net sales results 59

6.21 Jan 10, 2017: Zimmer Biomet Announces Fourth Quarter and Full-Year 2016 Preliminary Sales Results 60

6.22 Dec 14, 2016: Zimmer Biomet Update on Product Supply Matters and Responsive Statement on Recently Completed FDA Inspection 61

6.23 Dec 12, 2016: Alphatec Holdings appoints new CEO 61

6.24 Dec 12, 2016: Alphatec Holdings Announces Board and Executive Leadership Changes 62

6.25 Nov 30, 2016: Graham Baker appointed Chief Financial Officer 65

6.26 Nov 22, 2016: Medtronic Reports Second Quarter Financial Results 65

6.27 Nov 16, 2016: Medtronic Releases FY16 Integrated Performance Report 68

6.28 Nov 15, 2016: CEVA to work with Medtronic for distribution facility construction 69

6.29 Nov 14, 2016: DJO Global Announces Appointment of Brady Shirley as President and Chief Executive Officer 69

6.30 Nov 09, 2016: Alphatec Holdings Announces Third Quarter 2016 Revenue and Financial Results 70

6.31 Nov 08, 2016: DJO Global Announces Financial Results for Third Quarter 73

6.32 Nov 03, 2016: Smith & Nephew Third Quarter 2016 Trading Report 74

6.33 Oct 31, 2016: Zimmer Biomet Reports Third Quarter 2016 Financial Results 76

6.34 Oct 31, 2016: Exactech Q3 Revenue Up 7% to $59.9 Million. Net Income up 10% to $3.2 Million. Diluted EPS $0.22 vs. $0.20. 77

6.35 Oct 27, 2016: Stryker reports third quarter 2016 results 78

6.36 Oct 05, 2016: Alphatec Holdings Announces Company Updates 79

6.37 Sep 15, 2016: Alphatec Holdings Announces Company Updates 80

6.38 Sep 15, 2016: Medtronic Names Mark Ploof Senior Vice President of Global Operations and Business Services 82

6.39 Sep 06, 2016: DJO Global Announces Appointment of Mike Eklund as Chief Operating Officer and Chief Financial Officer 82

6.40 Aug 25, 2016: Medtronic Reports First Quarter Financial Results 83

6.41 Aug 01, 2016: Exactech Q2 Revenue Up 8% to $66.1 Million; Net Income up 20% to $4.4 Million; Diluted EPS $0.31 vs. $0.26 86

6.42 Jul 28, 2016: Smith & Nephew Second Quarter Trading and First Half 2016 Results 87

6.43 Jul 28, 2016: Zimmer Biomet Reports Second Quarter 2016 Financial Results 90

6.44 Jul 28, 2016: DJO Global Announces Financial Results for Second Quarter 2016 91

6.45 Jul 21, 2016: Stryker reports second quarter 2016 results 92

6.46 Jul 11, 2016: CFO to leave Smith & Nephew in early 2017 93

6.47 Jul 06, 2016: Merit Medical Systems Acquires DFINE for USD97.5 Million 94

6.48 Jun 30, 2016: NuVasive Agrees to Settle Patent Litigation With Medtronic 94

6.49 Jun 13, 2016: Zimmer Biomet Raises USD1.28 Billion in Public Offering of Shares 95

6.50 Jun 07, 2016: Zimmer Biomet Raises USD532 Million in Public Offering of 2.42% Notes Due 2026 95

6.51 Jun 07, 2016: Zimmer Biomet Raises USD532 Million in Public Offering of 1.4% Notes Due 2022 96

6.52 Jun 06, 2016: Medtronic Outlines Future Growth Vision at Investor Day 96

6.53 Jun 01, 2016: Osseon Expands Its Independent Distribution Network 97

6.54 May 31, 2016: Medtronic Reports Fourth Quarter and Fiscal Year 2016 Financial Results 97

6.55 May 10, 2016: DJO Global Announces Financial Results for First Quarter 2016 100

6.56 Apr 20, 2016: Stryker reports first quarter 2016 results 101

6.57 Mar 31, 2016: GRAFTYS strengthens its management and operations 102

7 Appendix 103

7.1 Methodology 103

7.2 About GlobalData 106

7.3 Contact Us 106

7.4 Disclaimer 106


List Of Figure

1.2 List of Figures

Figure 1: Orthopedic Bone Cement-Pipeline Products by Stage of Development 8

Figure 2: Orthopedic Bone Cement-Pipeline Products by Segment 9

Figure 3: Orthopedic Bone Cement-Pipeline Products by Territory 10

Figure 4: Orthopedic Bone Cement-Pipeline Products by Regulatory Path 11

Figure 5: Orthopedic Bone Cement-Pipeline Products by Estimated Approval Date 12


List Of Table

1.1 List of Tables

Table 1: Orthopedic Bone Cement-Pipeline Products by Stage of Development 8

Table 2: Orthopedic Bone Cement-Pipeline Products by Segment 9

Table 3: Orthopedic Bone Cement-Pipeline Products by Territory 10

Table 4: Orthopedic Bone Cement-Pipeline Products by Regulatory Path 11

Table 5: Orthopedic Bone Cement-Pipeline Products by Estimated Approval Date 12

Table 6: Bone Cement Companies-Pipeline Products by Stage of Development 13

Table 7: Orthopedic Bone Cement-Pipeline Products by Stage of Development 14

Table 8: aap Implantate AG Pipeline Products & Ongoing Clinical Trials Overview 15

Table 9: Ag Cement-Product Status 15

Table 10: Ag Cement-Product Description 16

Table 11: Biofix Medical Technologies Pipeline Products & Ongoing Clinical Trials Overview 17

Table 12: Injectable Glass Ionomer Cement-Product Status 17

Table 13: Injectable Glass Ionomer Cement-Product Description 17

Table 14: Bone-Rad Therapeutics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 18

Table 15: Spine-Rad Brachytherapy Bone Cement-Product Status 18

Table 16: Spine-Rad Brachytherapy Bone Cement-Product Description 18

Table 17: DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview 19

Table 18: Statin Eluting Bone Cements-Product Status 19

Table 19: Statin Eluting Bone Cements-Product Description 19

Table 20: Exactech Inc Pipeline Products & Ongoing Clinical Trials Overview 20

Table 21: Bone Cement-Product Status 20

Table 22: Bone Cement-Product Description 20

Table 23: Graftys SA Pipeline Products & Ongoing Clinical Trials Overview 21

Table 24: GRFT-M03-Product Status 21

Table 25: GRFT-M03-Product Description 21

Table 26: GRFT-M05-Product Status 22

Table 27: GRFT-M05-Product Description 22

Table 28: Meta Biomed Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 23

Table 29: Bone Cement-Product Status 23

Table 30: Bone Cement-Product Description 23

Table 31: Onbone Oy Pipeline Products & Ongoing Clinical Trials Overview 24

Table 32: BIOCEMENT-Product Status 24

Table 33: BIOCEMENT-Product Description 24

Table 34: Osseon Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 25

Table 35: Monetite-Based Injectable Orthopaedic Cement-Product Status 25

Table 36: Monetite-Based Injectable Orthopaedic Cement-Product Description 25

Table 37: Ozics AG Pipeline Products & Ongoing Clinical Trials Overview 26

Table 38: CompO6 Bone Reinforcement Composite-Product Status 26

Table 39: CompO6 Bone Reinforcement Composite-Product Description 26

Table 40: CompO6 Reinforced Bone Composite-Osteoporotic Fractures-Product Status 27

Table 41: CompO6 Reinforced Bone Composite-Osteoporotic Fractures-Product Description 27

Table 42: Queen's University Belfast Pipeline Products & Ongoing Clinical Trials Overview 28

Table 43: Spinal Cement-Product Status 28

Table 44: Spinal Cement-Product Description 28

Table 45: Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 29

Table 46: BioCaS-Product Status 29

Table 47: BioCaS-Product Description 29

Table 48: Bone Cement-Product Status 30

Table 49: Bone Cement-Product Description 30

Table 50: Injectable Calcium Phosphate Cement-Product Status 30

Table 51: Injectable Calcium Phosphate Cement-Product Description 31

Table 52: Teknimed SA Pipeline Products & Ongoing Clinical Trials Overview 32

Table 53: Cemfix 1-Product Status 32

Table 54: Cemfix 1-Product Description 32

Table 55: Cemfix 3-Product Status 33

Table 56: Cemfix 3-Product Description 33

Table 57: University of Limerick Pipeline Products & Ongoing Clinical Trials Overview 34

Table 58: Bioactive Adhesive Cement-Product Status 34

Table 59: Bioactive Adhesive Cement-Product Description 34

Table 60: Dual Calcium Phosphate Paste System-Product Status 34

Table 61: Dual Calcium Phosphate Paste System-Product Description 35

Table 62: Heracap-Product Status 35

Table 63: Heracap-Product Description 35

Table 64: Zimmer Biomet Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 36

Table 65: Cobalt Stage One Acrylic Spacer Cement-Product Status 36

Table 66: Cobalt Stage One Acrylic Spacer Cement-Product Description 36

Table 67: Glossary 105

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Companies

aap Implantate AG, Biofix Medical Technologies, Bone-Rad Therapeutics, Inc., DePuy Synthes Inc, Exactech Inc, Graftys SA, Meta Biomed Co Ltd, Onbone Oy, Osseon Therapeutics Inc, Ozics AG, Queen's University Belfast, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Teknimed SA, University of Limerick, Zimmer Biomet Holdings Inc