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Pharmaceuticals Top 5 Emerging Markets Industry Guide 2014-2023

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Pharmaceuticals Top 5 Emerging Markets Industry Guide 2014-2023

Summary

The Emerging 5 Pharmaceuticals industry profile provides top-line qualitative and quantitative summary information including: market share, market size (value 2014-18, and forecast to 2023). The profile also contains descriptions of the leading players including key financial metrics and analysis of competitive pressures within the market.

Essential resource for top-line data and analysis covering the emerging five pharmaceuticals market. Includes market size data, textual and graphical analysis of market growth trends and leading companies.

Key Highlights

- These countries contributed USD 222.4 billion to the global pharmaceuticals industry in 2018, with a compound annual growth rate (CAGR) of 7.7% between 2007 and 2011. The top 5 emerging countries are expected to reach a value of USD 369.3 billion in 2023, with a CAGR of 10.7% over the 2018-23 period.

- Within the pharmaceuticals industry, China is the leading country among the top 5 emerging nations, with market revenues of USD 132.9 billion in 2018. This was followed by India and Brazil with a value of USD 38.2 and USD 23.6 billion, respectively.

- China is expected to lead the pharmaceuticals industry in the top five emerging nations, with a value of USD 234.7 billion in 2023, followed by India and Brazil with expected values of USD 72.7 and USD 27.9 billion, respectively.

Scope

- Save time carrying out entry-level research by identifying the size, growth, and leading players in the emerging five pharmaceuticals market

- Use the Five Forces analysis to determine the competitive intensity and therefore attractiveness of the emerging five pharmaceuticals market

- Leading company profiles reveal details of key pharmaceuticals market players' emerging five operations and financial performance

- Add weight to presentations and pitches by understanding the future growth prospects of the emerging five pharmaceuticals market with five year forecasts

- Compares data from Brazil, China, India, Mexico and South Africa, alongside individual chapters on each country

Reasons to buy

- What was the size of the emerging five pharmaceuticals market by value in 2018?

- What will be the size of the emerging five pharmaceuticals market in 2023?

- What factors are affecting the strength of competition in the emerging five pharmaceuticals market?

- How has the market performed over the last five years?

- Who are the top competitors in the emerging five pharmaceuticals market?

READ MORE

Table Of Content

Scope

Table of Contents

Introduction

What is this report about?

Who is the target reader?

How to use this report

Definitions

Top 5 Emerging Countries Pharmaceuticals

Industry Outlook

Pharmaceuticals in South Africa

Market Overview

Market Data

Market Segmentation

Market outlook

Five forces analysis

Macroeconomic indicators

Pharmaceuticals in Brazil

Market Overview

Market Data

Market Segmentation

Market outlook

Five forces analysis

Macroeconomic indicators

Pharmaceuticals in China

Market Overview

Market Data

Market Segmentation

Market outlook

Five forces analysis

Macroeconomic indicators

Pharmaceuticals in India

Market Overview

Market Data

Market Segmentation

Market outlook

Five forces analysis

Macroeconomic indicators

Pharmaceuticals in Mexico

Market Overview

Market Data

Market Segmentation

Market outlook

Five forces analysis

Macroeconomic indicators

Company Profiles

Leading Companies

Appendix

Methodology

About MarketLine


List Of Figure

List of Figures

Figure 1: Top 5 emerging countries pharmaceuticals industry, revenue (USD bn), 2014-23

Figure 2: Top 5 emerging countries pharmaceuticals industry, revenue (USD bn), 2014-18

Figure 3: Top 5 emerging countries pharmaceuticals industry forecast, revenue (USD bn), 2018-23

Figure 4: South Africa pharmaceuticals market value: USD billion, 2014-18

Figure 5: South Africa pharmaceuticals market geography segmentation: % share, by value, 2018

Figure 6: South Africa pharmaceuticals market share: % share, by value, 2018

Figure 7: South Africa pharmaceuticals market value forecast: USD billion, 2018-23

Figure 8: Forces driving competition in the pharmaceuticals market in South Africa, 2018

Figure 9: Drivers of buyer power in the pharmaceuticals market in South Africa, 2018

Figure 10: Drivers of supplier power in the pharmaceuticals market in South Africa, 2018

Figure 11: Factors influencing the likelihood of new entrants in the pharmaceuticals market in South Africa, 2018

Figure 12: Factors influencing the threat of substitutes in the pharmaceuticals market in South Africa, 2018

Figure 13: Drivers of degree of rivalry in the pharmaceuticals market in South Africa, 2018

Figure 14: Brazil pharmaceuticals market value: USD billion, 2014-18

Figure 15: Brazil pharmaceuticals market geography segmentation: % share, by value, 2018

Figure 16: Brazil pharmaceuticals market share: % share, by value, 2018

Figure 17: Brazil pharmaceuticals market value forecast: USD billion, 2018-23

Figure 18: Forces driving competition in the pharmaceuticals market in Brazil, 2018

Figure 19: Drivers of buyer power in the pharmaceuticals market in Brazil, 2018

Figure 20: Drivers of supplier power in the pharmaceuticals market in Brazil, 2018

Figure 21: Factors influencing the likelihood of new entrants in the pharmaceuticals market in Brazil, 2018

Figure 22: Factors influencing the threat of substitutes in the pharmaceuticals market in Brazil, 2018

Figure 23: Drivers of degree of rivalry in the pharmaceuticals market in Brazil, 2018

Figure 24: China pharmaceuticals market value: USD billion, 2014-18

Figure 25: China pharmaceuticals market geography segmentation: % share, by value, 2018

Figure 26: China pharmaceuticals market share: % share, by value, 2018

Figure 27: China pharmaceuticals market value forecast: USD billion, 2018-23

Figure 28: Forces driving competition in the pharmaceuticals market in China, 2018

Figure 29: Drivers of buyer power in the pharmaceuticals market in China, 2018

Figure 30: Drivers of supplier power in the pharmaceuticals market in China, 2018

Figure 31: Factors influencing the likelihood of new entrants in the pharmaceuticals market in China, 2018

Figure 32: Factors influencing the threat of substitutes in the pharmaceuticals market in China, 2018

Figure 33: Drivers of degree of rivalry in the pharmaceuticals market in China, 2018

Figure 34: India pharmaceuticals market value: USD billion, 2014-18

Figure 35: India pharmaceuticals market geography segmentation: % share, by value, 2018

Figure 36: India pharmaceuticals market share: % share, by value, 2018

Figure 37: India pharmaceuticals market value forecast: USD billion, 2018-23

Figure 38: Forces driving competition in the pharmaceuticals market in India, 2018

Figure 39: Drivers of buyer power in the pharmaceuticals market in India, 2018

Figure 40: Drivers of supplier power in the pharmaceuticals market in India, 2018

Figure 41: Factors influencing the likelihood of new entrants in the pharmaceuticals market in India, 2018

Figure 42: Factors influencing the threat of substitutes in the pharmaceuticals market in India, 2018

Figure 43: Drivers of degree of rivalry in the pharmaceuticals market in India, 2018

Figure 44: Mexico pharmaceuticals market value: USD billion, 2014-18

Figure 45: Mexico pharmaceuticals market geography segmentation: % share, by value, 2018

Figure 46: Mexico pharmaceuticals market share: % share, by value, 2018

Figure 47: Mexico pharmaceuticals market value forecast: USD billion, 2018-23

Figure 48: Forces driving competition in the pharmaceuticals market in Mexico, 2018

Figure 49: Drivers of buyer power in the pharmaceuticals market in Mexico, 2018

Figure 50: Drivers of supplier power in the pharmaceuticals market in Mexico, 2018

Figure 51: Factors influencing the likelihood of new entrants in the pharmaceuticals market in Mexico, 2018

Figure 52: Factors influencing the threat of substitutes in the pharmaceuticals market in Mexico, 2018

Figure 53: Drivers of degree of rivalry in the pharmaceuticals market in Mexico, 2018

Figure 54: Adcock Ingram Holdings Ltd: revenues & profitability

Figure 55: Adcock Ingram Holdings Ltd: assets & liabilities

Figure 56: Aspen Pharmacare Holdings Ltd: revenues & profitability

Figure 57: Aspen Pharmacare Holdings Ltd: assets & liabilities

Figure 58: Sanofi SA: revenues & profitability

Figure 59: Sanofi SA: assets & liabilities

Figure 60: Shanghai Pharmaceuticals: revenues & profitability


List Of Table

List of Tables

Table 1: Top 5 emerging countries pharmaceuticals industry, revenue (USD bn), 2014-23

Table 2: Top 5 emerging countries pharmaceuticals industry, revenue (USD bn), 2014-18

Table 3: Top 5 emerging countries pharmaceuticals industry forecast, revenue (USD bn), 2018-23

Table 4: South Africa pharmaceuticals market value: USD billion, 2014-18

Table 5: South Africa pharmaceuticals market geography segmentation: USD billion, 2018

Table 6: South Africa pharmaceuticals market share: % share, by value, 2018

Table 7: South Africa pharmaceuticals market value forecast: USD billion, 2018-23

Table 8: South Africa size of population (million), 2014-18

Table 9: South Africa gdp (constant 2005 prices, USD billion), 2014-18

Table 10: South Africa gdp (current prices, USD billion), 2014-18

Table 11: South Africa inflation, 2014-18

Table 12: South Africa consumer price index (absolute), 2014-18

Table 13: South Africa exchange rate, 2014-18

Table 14: Brazil pharmaceuticals market value: USD billion, 2014-18

Table 15: Brazil pharmaceuticals market geography segmentation: USD billion, 2018

Table 16: Brazil pharmaceuticals market share: % share, by value, 2018

Table 17: Brazil pharmaceuticals market value forecast: USD billion, 2018-23

Table 18: Brazil size of population (million), 2014-18

Table 19: Brazil gdp (constant 2005 prices, USD billion), 2014-18

Table 20: Brazil gdp (current prices, USD billion), 2014-18

Table 21: Brazil inflation, 2014-18

Table 22: Brazil consumer price index (absolute), 2014-18

Table 23: Brazil exchange rate, 2014-18

Table 24: China pharmaceuticals market value: USD billion, 2014-18

Table 25: China pharmaceuticals market geography segmentation: USD billion, 2018

Table 26: China pharmaceuticals market share: % share, by value, 2018

Table 27: China pharmaceuticals market value forecast: USD billion, 2018-23

Table 28: China size of population (million), 2014-18

Table 29: China gdp (constant 2005 prices, USD billion), 2014-18

Table 30: China gdp (current prices, USD billion), 2014-18

Table 31: China inflation, 2014-18

Table 32: China consumer price index (absolute), 2014-18

Table 33: China exchange rate, 2014-18

Table 34: India pharmaceuticals market value: USD billion, 2014-18

Table 35: India pharmaceuticals market geography segmentation: USD billion, 2018

Table 36: India pharmaceuticals market share: % share, by value, 2018

Table 37: India pharmaceuticals market value forecast: USD billion, 2018-23

Table 38: India size of population (million), 2014-18

Table 39: India gdp (constant 2005 prices, USD billion), 2014-18

Table 40: India gdp (current prices, USD billion), 2014-18

Table 41: India inflation, 2014-18

Table 42: India consumer price index (absolute), 2014-18

Table 43: India exchange rate, 2014-18

Table 44: Mexico pharmaceuticals market value: USD billion, 2014-18

Table 45: Mexico pharmaceuticals market geography segmentation: USD billion, 2018

Table 46: Mexico pharmaceuticals market share: % share, by value, 2018

Table 47: Mexico pharmaceuticals market value forecast: USD billion, 2018-23

Table 48: Mexico size of population (million), 2014-18

Table 49: Mexico gdp (constant 2005 prices, USD billion), 2014-18

Table 50: Mexico gdp (current prices, USD billion), 2014-18

Table 51: Mexico inflation, 2014-18

Table 52: Mexico consumer price index (absolute), 2014-18

Table 53: Mexico exchange rate, 2014-18

Table 54: Adcock Ingram Holdings Ltd: key facts

Table 55: Adcock Ingram Holdings Ltd: key financials (USD )

Table 56: Adcock Ingram Holdings Ltd: key financials (ZAR)

Table 57: Adcock Ingram Holdings Ltd: key financial ratios

Table 58: Aspen Pharmacare Holdings Ltd: key facts

Table 59: Aspen Pharmacare Holdings Ltd: key financials (USD )

Table 60: Aspen Pharmacare Holdings Ltd: key financials (ZAR)

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Company Profile

Company Profile Title

Pharmaceuticals Top 5 Emerging Markets Industry Guide 2014-2023

Summary

The Emerging 5 Pharmaceuticals industry profile provides top-line qualitative and quantitative summary information including: market share, market size (value 2014-18, and forecast to 2023). The profile also contains descriptions of the leading players including key financial metrics and analysis of competitive pressures within the market.

Essential resource for top-line data and analysis covering the emerging five pharmaceuticals market. Includes market size data, textual and graphical analysis of market growth trends and leading companies.

Key Highlights

- These countries contributed USD 222.4 billion to the global pharmaceuticals industry in 2018, with a compound annual growth rate (CAGR) of 7.7% between 2007 and 2011. The top 5 emerging countries are expected to reach a value of USD 369.3 billion in 2023, with a CAGR of 10.7% over the 2018-23 period.

- Within the pharmaceuticals industry, China is the leading country among the top 5 emerging nations, with market revenues of USD 132.9 billion in 2018. This was followed by India and Brazil with a value of USD 38.2 and USD 23.6 billion, respectively.

- China is expected to lead the pharmaceuticals industry in the top five emerging nations, with a value of USD 234.7 billion in 2023, followed by India and Brazil with expected values of USD 72.7 and USD 27.9 billion, respectively.

Scope

- Save time carrying out entry-level research by identifying the size, growth, and leading players in the emerging five pharmaceuticals market

- Use the Five Forces analysis to determine the competitive intensity and therefore attractiveness of the emerging five pharmaceuticals market

- Leading company profiles reveal details of key pharmaceuticals market players' emerging five operations and financial performance

- Add weight to presentations and pitches by understanding the future growth prospects of the emerging five pharmaceuticals market with five year forecasts

- Compares data from Brazil, China, India, Mexico and South Africa, alongside individual chapters on each country

Reasons to buy

- What was the size of the emerging five pharmaceuticals market by value in 2018?

- What will be the size of the emerging five pharmaceuticals market in 2023?

- What factors are affecting the strength of competition in the emerging five pharmaceuticals market?

- How has the market performed over the last five years?

- Who are the top competitors in the emerging five pharmaceuticals market?

READ MORE

Scope

Table of Contents

Introduction

What is this report about?

Who is the target reader?

How to use this report

Definitions

Top 5 Emerging Countries Pharmaceuticals

Industry Outlook

Pharmaceuticals in South Africa

Market Overview

Market Data

Market Segmentation

Market outlook

Five forces analysis

Macroeconomic indicators

Pharmaceuticals in Brazil

Market Overview

Market Data

Market Segmentation

Market outlook

Five forces analysis

Macroeconomic indicators

Pharmaceuticals in China

Market Overview

Market Data

Market Segmentation

Market outlook

Five forces analysis

Macroeconomic indicators

Pharmaceuticals in India

Market Overview

Market Data

Market Segmentation

Market outlook

Five forces analysis

Macroeconomic indicators

Pharmaceuticals in Mexico

Market Overview

Market Data

Market Segmentation

Market outlook

Five forces analysis

Macroeconomic indicators

Company Profiles

Leading Companies

Appendix

Methodology

About MarketLine


List Of Figure

List of Figures

Figure 1: Top 5 emerging countries pharmaceuticals industry, revenue (USD bn), 2014-23

Figure 2: Top 5 emerging countries pharmaceuticals industry, revenue (USD bn), 2014-18

Figure 3: Top 5 emerging countries pharmaceuticals industry forecast, revenue (USD bn), 2018-23

Figure 4: South Africa pharmaceuticals market value: USD billion, 2014-18

Figure 5: South Africa pharmaceuticals market geography segmentation: % share, by value, 2018

Figure 6: South Africa pharmaceuticals market share: % share, by value, 2018

Figure 7: South Africa pharmaceuticals market value forecast: USD billion, 2018-23

Figure 8: Forces driving competition in the pharmaceuticals market in South Africa, 2018

Figure 9: Drivers of buyer power in the pharmaceuticals market in South Africa, 2018

Figure 10: Drivers of supplier power in the pharmaceuticals market in South Africa, 2018

Figure 11: Factors influencing the likelihood of new entrants in the pharmaceuticals market in South Africa, 2018

Figure 12: Factors influencing the threat of substitutes in the pharmaceuticals market in South Africa, 2018

Figure 13: Drivers of degree of rivalry in the pharmaceuticals market in South Africa, 2018

Figure 14: Brazil pharmaceuticals market value: USD billion, 2014-18

Figure 15: Brazil pharmaceuticals market geography segmentation: % share, by value, 2018

Figure 16: Brazil pharmaceuticals market share: % share, by value, 2018

Figure 17: Brazil pharmaceuticals market value forecast: USD billion, 2018-23

Figure 18: Forces driving competition in the pharmaceuticals market in Brazil, 2018

Figure 19: Drivers of buyer power in the pharmaceuticals market in Brazil, 2018

Figure 20: Drivers of supplier power in the pharmaceuticals market in Brazil, 2018

Figure 21: Factors influencing the likelihood of new entrants in the pharmaceuticals market in Brazil, 2018

Figure 22: Factors influencing the threat of substitutes in the pharmaceuticals market in Brazil, 2018

Figure 23: Drivers of degree of rivalry in the pharmaceuticals market in Brazil, 2018

Figure 24: China pharmaceuticals market value: USD billion, 2014-18

Figure 25: China pharmaceuticals market geography segmentation: % share, by value, 2018

Figure 26: China pharmaceuticals market share: % share, by value, 2018

Figure 27: China pharmaceuticals market value forecast: USD billion, 2018-23

Figure 28: Forces driving competition in the pharmaceuticals market in China, 2018

Figure 29: Drivers of buyer power in the pharmaceuticals market in China, 2018

Figure 30: Drivers of supplier power in the pharmaceuticals market in China, 2018

Figure 31: Factors influencing the likelihood of new entrants in the pharmaceuticals market in China, 2018

Figure 32: Factors influencing the threat of substitutes in the pharmaceuticals market in China, 2018

Figure 33: Drivers of degree of rivalry in the pharmaceuticals market in China, 2018

Figure 34: India pharmaceuticals market value: USD billion, 2014-18

Figure 35: India pharmaceuticals market geography segmentation: % share, by value, 2018

Figure 36: India pharmaceuticals market share: % share, by value, 2018

Figure 37: India pharmaceuticals market value forecast: USD billion, 2018-23

Figure 38: Forces driving competition in the pharmaceuticals market in India, 2018

Figure 39: Drivers of buyer power in the pharmaceuticals market in India, 2018

Figure 40: Drivers of supplier power in the pharmaceuticals market in India, 2018

Figure 41: Factors influencing the likelihood of new entrants in the pharmaceuticals market in India, 2018

Figure 42: Factors influencing the threat of substitutes in the pharmaceuticals market in India, 2018

Figure 43: Drivers of degree of rivalry in the pharmaceuticals market in India, 2018

Figure 44: Mexico pharmaceuticals market value: USD billion, 2014-18

Figure 45: Mexico pharmaceuticals market geography segmentation: % share, by value, 2018

Figure 46: Mexico pharmaceuticals market share: % share, by value, 2018

Figure 47: Mexico pharmaceuticals market value forecast: USD billion, 2018-23

Figure 48: Forces driving competition in the pharmaceuticals market in Mexico, 2018

Figure 49: Drivers of buyer power in the pharmaceuticals market in Mexico, 2018

Figure 50: Drivers of supplier power in the pharmaceuticals market in Mexico, 2018

Figure 51: Factors influencing the likelihood of new entrants in the pharmaceuticals market in Mexico, 2018

Figure 52: Factors influencing the threat of substitutes in the pharmaceuticals market in Mexico, 2018

Figure 53: Drivers of degree of rivalry in the pharmaceuticals market in Mexico, 2018

Figure 54: Adcock Ingram Holdings Ltd: revenues & profitability

Figure 55: Adcock Ingram Holdings Ltd: assets & liabilities

Figure 56: Aspen Pharmacare Holdings Ltd: revenues & profitability

Figure 57: Aspen Pharmacare Holdings Ltd: assets & liabilities

Figure 58: Sanofi SA: revenues & profitability

Figure 59: Sanofi SA: assets & liabilities

Figure 60: Shanghai Pharmaceuticals: revenues & profitability


List Of Table

List of Tables

Table 1: Top 5 emerging countries pharmaceuticals industry, revenue (USD bn), 2014-23

Table 2: Top 5 emerging countries pharmaceuticals industry, revenue (USD bn), 2014-18

Table 3: Top 5 emerging countries pharmaceuticals industry forecast, revenue (USD bn), 2018-23

Table 4: South Africa pharmaceuticals market value: USD billion, 2014-18

Table 5: South Africa pharmaceuticals market geography segmentation: USD billion, 2018

Table 6: South Africa pharmaceuticals market share: % share, by value, 2018

Table 7: South Africa pharmaceuticals market value forecast: USD billion, 2018-23

Table 8: South Africa size of population (million), 2014-18

Table 9: South Africa gdp (constant 2005 prices, USD billion), 2014-18

Table 10: South Africa gdp (current prices, USD billion), 2014-18

Table 11: South Africa inflation, 2014-18

Table 12: South Africa consumer price index (absolute), 2014-18

Table 13: South Africa exchange rate, 2014-18

Table 14: Brazil pharmaceuticals market value: USD billion, 2014-18

Table 15: Brazil pharmaceuticals market geography segmentation: USD billion, 2018

Table 16: Brazil pharmaceuticals market share: % share, by value, 2018

Table 17: Brazil pharmaceuticals market value forecast: USD billion, 2018-23

Table 18: Brazil size of population (million), 2014-18

Table 19: Brazil gdp (constant 2005 prices, USD billion), 2014-18

Table 20: Brazil gdp (current prices, USD billion), 2014-18

Table 21: Brazil inflation, 2014-18

Table 22: Brazil consumer price index (absolute), 2014-18

Table 23: Brazil exchange rate, 2014-18

Table 24: China pharmaceuticals market value: USD billion, 2014-18

Table 25: China pharmaceuticals market geography segmentation: USD billion, 2018

Table 26: China pharmaceuticals market share: % share, by value, 2018

Table 27: China pharmaceuticals market value forecast: USD billion, 2018-23

Table 28: China size of population (million), 2014-18

Table 29: China gdp (constant 2005 prices, USD billion), 2014-18

Table 30: China gdp (current prices, USD billion), 2014-18

Table 31: China inflation, 2014-18

Table 32: China consumer price index (absolute), 2014-18

Table 33: China exchange rate, 2014-18

Table 34: India pharmaceuticals market value: USD billion, 2014-18

Table 35: India pharmaceuticals market geography segmentation: USD billion, 2018

Table 36: India pharmaceuticals market share: % share, by value, 2018

Table 37: India pharmaceuticals market value forecast: USD billion, 2018-23

Table 38: India size of population (million), 2014-18

Table 39: India gdp (constant 2005 prices, USD billion), 2014-18

Table 40: India gdp (current prices, USD billion), 2014-18

Table 41: India inflation, 2014-18

Table 42: India consumer price index (absolute), 2014-18

Table 43: India exchange rate, 2014-18

Table 44: Mexico pharmaceuticals market value: USD billion, 2014-18

Table 45: Mexico pharmaceuticals market geography segmentation: USD billion, 2018

Table 46: Mexico pharmaceuticals market share: % share, by value, 2018

Table 47: Mexico pharmaceuticals market value forecast: USD billion, 2018-23

Table 48: Mexico size of population (million), 2014-18

Table 49: Mexico gdp (constant 2005 prices, USD billion), 2014-18

Table 50: Mexico gdp (current prices, USD billion), 2014-18

Table 51: Mexico inflation, 2014-18

Table 52: Mexico consumer price index (absolute), 2014-18

Table 53: Mexico exchange rate, 2014-18

Table 54: Adcock Ingram Holdings Ltd: key facts

Table 55: Adcock Ingram Holdings Ltd: key financials (USD )

Table 56: Adcock Ingram Holdings Ltd: key financials (ZAR)

Table 57: Adcock Ingram Holdings Ltd: key financial ratios

Table 58: Aspen Pharmacare Holdings Ltd: key facts

Table 59: Aspen Pharmacare Holdings Ltd: key financials (USD )

Table 60: Aspen Pharmacare Holdings Ltd: key financials (ZAR)

Single User License:
Report can be used by individual purchaser only

Site License: 
Report can be shared by unlimited users within one corporate location, e.g. a regional office

Corporate User License:  
Report can be shared globally by unlimited users within the purchasing corporation e.g. all employees of a single company

To know more information on Purchase by Section, please send a mail to support@kenresearch.com

INQUIRE FOR COVID-19 IMPACT ANALYSIS